Every year, 500 000 people die from NTDs, 627 000 from malaria and 1.1 million from tuberculosis. These diseases perpetuate the cycle of poverty. They cause debilitating chronic conditions that impede an individual’s economic productivity. In children, these infections result in malnutrition, cognitive impairment, stunted growth and an inability to attend school. In pregnant mothers, anaemia results in poor birth outcomes. As a global community of innovators, we can cast the spotlight on these diseases and highlight high impact solutions that are improving the care delivered to these communities.